Adopting new memory technologies such as Persistent Memory and CXL-attached Memory is a challenge for software. While libraries and frameworks (such as PMDK) can help developers build new software around emerging technology, legacy software faces a more severe challenge. At IBM Research Almaden we are exploring a new approach to managing heterogeneous memory in the context of Python. Our solution, PyMM, focuses on ease-of-use and is aimed primarily at the data science community. This talk will outline PyMM and discuss how it is being used to manage Intel Optane persistent memory.