Abstract: DNA data storage is an attractive option for digital data storage because of its extreme density, durability and eternal relevance. This is especially attractive when contrasted with the exponential growth in world-wide digital data production. In this talk we will present our efforts in building an end-to-end system, from the computational component of encoding and decoding to the molecular biology component of random access, sequencing and fluidics automation. We will also discuss some early efforts in building a hybrid electronic/molecular computer system that can offer more than just data storage, for example, image similarity search.