Vector database indexing and search, and eCommerce usage of GNNs would be constrained in size if they had to fit in the few terabytes of storage of a single node. Data set sizes are trending beyond what will fit in the combined memory capacity of a whole rack of GPUs and CPUs. To meet the needs of both single-node and rack-scale enterprise and hyperscaler customers, there's a need to scale up to storage, rather than just scaling out more. We'll show fresh results for WholeGraph and cuVS at 10-trillion scale, along with the ecosystem prototypes that light the path toward commercial deployment.