Today, information is being digitized on a massive scale, by servers in datacenters, by mobile devices, and by networks of sensors everywhere around us. Artificial intelligence techniques and ubiquitous processing power are making it possible to mine this massive ocean of data; however, integral to harnessing this data as knowledge is the ability to store it for long periods of time.

DNA Sequencing using Sequencing-by-synthesis (SBS) technology is today responsible for the majority of sequencing done worldwide. This presentation will cover the fundamentals behind SBS, the steps involved in going from a DNA sample to data, and the current state of art of sequencing platforms. The presentation will end by discussing how DNA sequencing can be applied to DNA-based data storage.